Description

Isocytidine is a nucleoside analog of cytidine, where the base is attached to the ribose sugar at the N1 position instead of the N3 position. This unique structural isomer is a valuable building block in organic synthesis and biochemical research. It serves as a critical intermediate for the development of novel pharmaceuticals, antiviral agents, and modified oligonucleotides. Key industries that utilize this high-purity compound include pharmaceutical R&D, biotechnology, and academic research institutions.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
• Oligonucleotide Synthesis: Serves as a modified nucleoside precursor for creating specialized DNA/RNA analogs with altered properties for diagnostic or therapeutic applications.
• Chemical Biology Probes: Incorporated into probes to study nucleic acid structure, function, and protein-nucleic acid interactions.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic & Industrial R&D: Fundamental research tool in medicinal chemistry and molecular biology for exploring new therapeutic modalities.

Basic Information

Product Name	Isocytidine
CAS No.	489-59-8
Molecular Formula	C9H13N3O5
Molecular Weight	243.22 g/mol
Synonyms	1-β-D-Ribofuranosylcytosine; 1-(β-D-Ribofuranosyl)cytosine; 1-Cytosyl-β-D-ribofuranose; Cytosine-1-β-D-ribofuranoside; NSC 72964; Isocytosine riboside; 1-Ribosylcytosine
EINECS	207-688-5

Quality Control

Our Isocytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent controls for residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity biochemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.