Description

Dimethoxanate is a pharmaceutical-grade active pharmaceutical ingredient (API) primarily recognized for its antitussive (cough-suppressing) properties. This compound is valued for its efficacy in formulating central cough suppressants for therapeutic use. It is essential for pharmaceutical manufacturers and research institutions developing cough and cold medications. Our supply ensures high purity and consistent quality for reliable formulation outcomes.

Application

• Pharmaceutical API: Primary active ingredient in prescription and over-the-counter antitussive (cough suppressant) formulations.
• Syrup and Tablet Manufacturing: Used in the production of solid oral dosage forms (tablets, capsules) and liquid syrups for cough relief.
• Clinical Research: Serves as a reference standard and key intermediate in pharmacological studies and drug development programs targeting the cough reflex.
• Veterinary Pharmaceuticals: Incorporated into medicinal products for managing cough in animals.
• Combination Drug Therapies: Formulated with other APIs such as expectorants or antihistamines in multi-symptom cold and flu medications.

Basic Information

Product Name	Dimethoxanate
CAS No.	477-93-0
Molecular Formula	C19H31NO3S
Molecular Weight	353.52 g/mol
Synonyms	Dimethoxanate Hydrochloride; Cotrane; 2-Dimethylaminoethoxyethyl 10H-Phenothiazine-10-carboxylate; 10H-Phenothiazine-10-carboxylic acid 2-(dimethylamino)ethyl ester; 10-Carbophenothiazine-2-dimethylaminoethyl ester; Tussidin; Peracon; Antitus; Tussizid
EINECS	207-522-6

Quality Control

Our Dimethoxanate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing to ensure it meets stringent pharmaceutical standards, including identity, purity, and impurity profile verification. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.