Description

7β-Hydroxycholest-4-Ene CAS NO 475-32-1 is a high-purity sterol derivative, specifically a hydroxylated cholesterol analog, serving as a critical intermediate in advanced organic synthesis. This compound is valued for its defined stereochemistry at the 7-beta position, making it essential for research and development in complex molecular construction. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on steroid chemistry, drug discovery, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies, enzyme inhibition assays, and receptor binding research.
• Steroid Chemistry Synthesis: Serves as a versatile starting material for the preparation of more complex, functionalized sterol derivatives and analogs.
• Academic & Discovery Chemistry: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Integrated into multi-step synthesis processes for high-value specialty chemicals with specific steroidal frameworks.

Basic Information

Product Name	7β-Hydroxycholest-4-Ene
CAS No.	475-32-1
Molecular Formula	C₂₇H₄₆O
Molecular Weight	386.66 g/mol
Synonyms	7β-Hydroxycholest-4-ene; (7β)-Cholest-4-ene-3β,7-diol; 7β-Hydroxycholesterol (common name for the 4-ene isomer); 3β,7β-Dihydroxycholest-4-ene; 7β-Hydroxy-δ⁴-cholestene; NSC 72178; 7β-Hydroxy-4-cholestene
EINECS	207-485-5

Quality Control

Our 7β-Hydroxycholest-4-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and specific tests for related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.