Description

3β-Hydroxy-5β-Bufa-14,16,20,22-Tetrenolide CAS NO 474-53-3 is a high-purity bufadienolide compound, a class of cardioactive steroids. This specialized intermediate is valued for its precise chemical structure, which is critical for advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents and in-depth pharmacological studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardioactive steroid derivatives and other specialized pharmaceutical compounds.
• Biochemical Research: Used as a reference standard or active agent in studies investigating Na+/K+-ATPase inhibition and related cardiac glycoside pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Preclinical Studies: Employed in in-vitro and in-vivo research models to explore potential therapeutic applications and mechanisms of action.

Basic Information

Product Name	3β-Hydroxy-5β-Bufa-14,16,20,22-Tetrenolide
CAS No.	474-53-3
Molecular Formula	C24H32O4
Molecular Weight	384.51 g/mol
Synonyms	Bufalin; 3β-Hydroxy-14,15β-epoxy-5β-bufa-20,22-dienolide; Bufadienolide A; NSC 83265; 3β,14-Dihydroxy-5β-bufa-20,22-dienolide; 3β-Hydroxy-5β-bufa-20,22-dienolide-14,15-oxide; 14,15-Epoxy-3β-hydroxy-5β-bufa-20,22-dienolide
EINECS	207-472-5

Quality Control

Our 3β-Hydroxy-5β-Bufa-14,16,20,22-Tetrenolide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect the product from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.