Description

(20S)-3Alpha-Amino-5Alpha-Pregnan-20-Ol is a high-purity, synthetic neurosteroid intermediate of significant pharmaceutical interest. This compound serves as a critical building block in the research and development of novel therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on neuroactive steroids and their analogs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of neurosteroids and related therapeutic compounds.
• Neurological Research: Used as a reference standard and active material in studies of GABA-A receptor modulation.
• Fine Chemical Synthesis: Building block for creating specialized steroid derivatives with targeted biological activity.
• Biochemical Assay Development: Employed in the development of screening assays for neurosteroid activity and metabolism.
• Academic & Contract Research: Essential material for fundamental research into steroid chemistry and neuropharmacology.

Basic Information

Item	Details
Product Name	(20S)-3Alpha-Amino-5Alpha-Pregnan-20-Ol
CAS No.	474-44-2
Molecular Formula	C21H37NO
Molecular Weight	319.53 g/mol
Synonyms	3α-Amino-5α-pregnan-20-ol; (3α,5α,20S)-Pregnan-20-ol-3-amine; 20S-Hydroxy-3α-amino-5α-pregnane; 3-Aminopregnanolone; Pregnanolone amine; Allopregnanolone amine derivative
EINECS	Contact for details

Quality Control

Our (20S)-3Alpha-Amino-5Alpha-Pregnan-20-Ol is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.