Description

(25R)-5β-Spirostane-1β,3β-Diol CAS NO 472-10-6 is a high-purity steroidal sapogenin derivative, specifically a dihydroxylated spirostane, serving as a critical advanced intermediate in pharmaceutical synthesis. Its defined stereochemistry and functional groups make it a valuable building block for the research and development of novel steroid-based therapeutics and bioactive compounds. This compound is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on steroid chemistry, hormone analogs, and specialized organic synthesis.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of steroid drugs, including potential anti-inflammatory, hormonal, or cardiovascular agents.
• Biochemical Research: Used as a reference standard or probe in steroid metabolism studies, receptor binding assays, and enzymatic pathway investigations.
• Fine Chemical Synthesis: Serves as a chiral precursor for the preparation of more complex steroidal structures with specific biological activities.
• Academic & Industrial R&D: Employed in discovery chemistry for creating novel chemical entities (NCEs) and exploring structure-activity relationships (SAR) in steroid-based compounds.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related steroid products.

Basic Information

Product Name	(25R)-5β-Spirostane-1β,3β-Diol
CAS No.	472-10-6
Molecular Formula	C27H44O4
Molecular Weight	432.64 g/mol
Synonyms	1β,3β-Dihydroxy-5β-spirostan; (25R)-Spirostane-1β,3β-diol; 5β-Spirostane-1β,3β-diol; Diosgenin derivative; Sarasapogenin derivative; (25R)-1β,3β-Dihydroxyspirostan-5β-ol; 472-10-6
EINECS	Contact for details

Quality Control

Our (25R)-5β-Spirostane-1β,3β-Diol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.