Description

Cinobufagin is a bioactive steroidal lactone (bufadienolide) isolated from traditional sources, serving as a key reference standard and active pharmaceutical ingredient. This high-purity compound is critical for ensuring quality control in pharmaceutical research and the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on oncology, cardiology, and natural product chemistry.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of related products in quality control laboratories.
• Biomedical Research: Serves as a key reagent in pharmacological studies investigating mechanisms of action, particularly in cancer cell research.
• Active Pharmaceutical Ingredient (API): Employed in the formulation development of investigational drugs and traditional medicine preparations.
• Analytical Chemistry: Acts as a critical calibration standard for HPLC, LC-MS, and other chromatographic methods.
• Biochemical Assays: Utilized in enzyme inhibition studies and other target-based screening assays.
• Natural Product Isolation & Synthesis: Functions as a marker compound for the standardization of botanical extracts and as a precursor in synthetic studies.

Basic Information

Product Name	Cinobufagin
CAS No.	470-37-1
Molecular Formula	C₂₆H₃₄O₆
Molecular Weight	442.55 g/mol
Synonyms	Cinobufagine; (3β,5β,16β)-3,14-Dihydroxy-19-oxobufa-20,22-dienolide; Bufogenin B; Arenobufagin; Venenobufagin; Ch'an Su constituent; Toad venom constituent
EINECS	Contact for details

Quality Control

Our Cinobufagin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for reference standards, and specifications can be tailored to meet specific pharmacopeial or internal quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.