Description

(25R)-5β-Spirostane-2β,3β-Diol is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex bioactive molecules. Its defined stereochemistry and diol functionality make it a valuable chiral building block for pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise, high-quality intermediates for steroid-based drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral precursor for the synthesis of steroidal drugs, including corticosteroids, hormones, and other bioactive agents.
• Research & Development: Used in academic and industrial R&D for studying steroid biosynthesis, metabolism, and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Serves as a starting material or intermediate in multi-step organic syntheses to create complex molecular architectures.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and compound identification via HPLC, GC-MS, or NMR.
• Biochemical Studies: Utilized in enzymatic and metabolic pathway studies related to steroidogenesis.

Basic Information

Product Name	(25R)-5β-Spirostane-2β,3β-Diol
CAS No.	469-97-6
Molecular Formula	C27H44O4
Molecular Weight	432.64 g/mol
Synonyms	2β,3β-Dihydroxyspirostan-5β-ol; (25R)-Spirostane-2β,3β-diol; 5β-Spirostane-2β,3β-diol; Diosgenin diol derivative; Tigogenin diol; (2β,3β,25R)-Spirostane-2,3-diol; 469-97-6; NSC 146061
EINECS	Contact for details

Quality Control

Our (25R)-5β-Spirostane-2β,3β-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is stable under these conditions but should be kept in a desiccator or under an inert atmosphere for long-term storage to maintain optimal quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.