Description

Epigriseofulvin CAS NO 469-49-8 is a stereoisomer of the well-known antifungal agent griseofulvin, characterized by its specific molecular configuration. This compound is of significant interest in pharmaceutical research and development for its potential biological activity and as a critical reference standard. It serves as a vital building block and analytical tool for scientists in the life sciences sector. Key industries that utilize this specialized chemical include pharmaceutical R&D, contract research organizations (CROs), and academic institutions focused on antifungal discovery and metabolic studies.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for quality control and analytical method development in antifungal drug manufacturing.
• Biochemical Research: Employed in studies investigating the structure-activity relationship (SAR) of griseofulvin derivatives and their mechanism of action against fungal pathogens.
• Metabolite Studies: Serves as a key intermediate or metabolite analog in pharmacokinetic and metabolic pathway research for antifungal therapies.
• Active Pharmaceutical Ingredient (API) Development: Acts as a starting material or intermediate in the synthesis and development of novel antifungal agents.
• Academic & Contract Research: Utilized in university laboratories and CROs for fundamental research on microtubule function and fungal cell biology.

Basic Information

Product Name	Epigriseofulvin
CAS No.	469-49-8
Molecular Formula	C17H17ClO6
Molecular Weight	352.77 g/mol
Synonyms	(+)-Epigriseofulvin; 7-Chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1'-(2'-methoxy-6'-methylcyclohex-2'-en-4'-one); Griseofulvin, epi-; 6'-Methyl-4,6,2'-trimethoxy-7-chlorogris-2'-en-3,4'-dione stereoisomer; NSC 345647; Epigriseofulvine
EINECS	Contact for details

Quality Control

Our Epigriseofulvin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a comprehensive Certificate of Analysis (COA). We adhere to relevant industry standards suitable for research and development applications, ensuring reliable and traceable material for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.