Description

Isotachysterol is a synthetic derivative of vitamin D, specifically a photoisomer of tachysterol, with the CAS registry number 469-06-7. This compound is a critical reference standard and research chemical used in the study of vitamin D metabolism, photochemistry, and receptor binding. It is primarily required by pharmaceutical R&D laboratories, analytical testing facilities, and academic research institutions investigating calciferol pathways and developing related therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quantifying vitamin D analogs and related sterols.
• Biochemical Research: Serves as a key intermediate and probe in studying the photoisomerization mechanisms and biological activity of vitamin D compounds.
• Metabolic Pathway Studies: Employed in research to elucidate the metabolic fate and activation pathways of vitamin D and its derivatives.
• Vitamin D Receptor (VDR) Research: Utilized as a ligand in binding assays and studies to understand VDR affinity and function.
• Chemical Synthesis: Acts as a specialized starting material or intermediate for the synthesis of novel vitamin D analogs and related steroidal compounds.

Basic Information

Product Name	Isotachysterol
CAS No.	469-06-7
Molecular Formula	C₂₈H₄₄O
Molecular Weight	396.65 g/mol
Synonyms	Isotachysterol; (5E,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraen-3β-ol; 3β-Hydroxy-9,10-seco-5,7,10(19),22-ergostatetraene; Vitamin D4 isomer; 5,6-trans-Tachysterol; Isotachysterol3; 5,6-trans-Vitamin D4
EINECS	Contact for details

Quality Control

Our Isotachysterol is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and specific optical rotation measurement, to ensure it meets the exacting standards required for research and reference applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This product is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.