Description

3β-Hydroxy-15-Oxo-5β,14α-Bufa-20,22-Dienolide is a high-purity, specialized bufadienolide compound of significant interest in advanced pharmaceutical research and development. This steroid derivative serves as a critical intermediate and reference standard for the synthesis and study of novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of new therapeutic agents and analytical methods. Our supply ensures consistent quality and reliable availability for your most demanding projects.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in analytical laboratories.
• Biochemical Research: Employed in pharmacological and toxicological studies to investigate the structure-activity relationships (SAR) of bufadienolides and cardiotonic steroids.
• Academic Research: Serves as a substrate or reagent in university and institutional research exploring natural product chemistry and biosynthesis pathways.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex organic molecules for high-value applications in life sciences.

Basic Information

Product Name	3β-Hydroxy-15-Oxo-5β,14α-Bufa-20,22-Dienolide
CAS No.	468-86-0
Molecular Formula	C₂₄H₃₂O₄
Molecular Weight	384.51 g/mol
Synonyms	3β-Hydroxy-14,15-epoxy-5β,14β-bufa-20,22-dienolide; 15-Oxobufalin; Bufa-20,22-dienolide, 3β-hydroxy-15-oxo-5β,14α-; 3β-Hydroxy-15-oxo-5β,14α-bufa-20,22-dienolide; 15-Oxo-3β-hydroxy-5β,14α-bufa-20,22-dienolide; 468-86-0; Bufadienolide derivative
EINECS	Contact for details

Quality Control

Every batch of 3β-Hydroxy-15-Oxo-5β,14α-Bufa-20,22-Dienolide is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.