Description

Corotoxigenin is a specialized cardiac glycoside aglycone, a key intermediate and reference standard in pharmaceutical research and development. Its precise chemical structure makes it invaluable for studying cardiac activity and synthesizing related therapeutic compounds. This high-purity material is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, well-characterized building blocks for drug discovery and quality control processes.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of cardiac glycoside APIs and related products.
• Biochemical Research: Serves as a critical tool in pharmacological studies to investigate the mechanism of action of cardiotonic steroids on the Na+/K+-ATPase pump.
• Organic Synthesis Intermediate: Acts as a key chiral precursor for the semi-synthesis of novel cardiac agents and other steroidal derivatives.
• Analytical Chemistry: Employed as an internal standard or calibrant in advanced chromatographic (HPLC, LC-MS) and spectroscopic methods for quantitative analysis.
• Academic Research: Utilized in university and institutional labs for teaching and fundamental research in medicinal chemistry and natural product chemistry.

Basic Information

Product Name	Corotoxigenin
CAS No.	468-20-2
Molecular Formula	C₂₃H₃₄O₇
Molecular Weight	422.51 g/mol
Synonyms	Corotoxigenin; 3β,5,14-Trihydroxy-19-oxo-5β-card-20(22)-enolide; 3β,5,14-Trihydroxy-19-oxocarda-20,22-dienolide; 19-Oxocorotoxigenin; NSC 169854; Strophanthidin 19-aldehyde
EINECS	Contact for details

Quality Control

Every batch of Corotoxigenin is produced and analyzed under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.