Description

19-Oxo-3β,14,16β-Trihydroxy-5β-Card-20(22)-Enolide is a high-purity, specialized cardenolide derivative, a key structural motif in bioactive natural products. This compound is of significant interest for its role as a critical intermediate in advanced pharmaceutical research and synthesis. It is primarily utilized by research institutions and pharmaceutical developers working on novel therapeutic agents, particularly in the areas of cardiology and oncology.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel cardiotonic steroids and other bioactive molecules.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development and quality control of related compounds.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of cardenolides and their interaction with biological targets like Na+/K+-ATPase.
• Preclinical Development: Acts as a starting material or intermediate in the discovery and development stages of new chemical entities (NCEs).

Basic Information

Item	Details
Product Name	19-Oxo-3β,14,16β-Trihydroxy-5β-Card-20(22)-Enolide
CAS No.	468-17-7
Molecular Formula	C₂₃H₃₄O₆
Molecular Weight	406.51 g/mol
Synonyms	19-Oxocardenolide; 3β,14,16β-Trihydroxy-19-oxo-5β-card-20(22)-enolide; 19-Oxo-3β,14β,16β-trihydroxy-5β-card-20(22)-enolide; 19-Oxodigitoxigenin; 19-Ketodigitoxigenin; 3β,14β,16β-Trihydroxy-19-oxo-5β,20(22)-cardenolide; Strophanthidin derivative
EINECS	Contact for details

Quality Control

Our 19-Oxo-3β,14,16β-Trihydroxy-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.