Description

Uzarigenin CAS NO 466-09-1 is a naturally occurring cardenolide aglycone, a key chemical scaffold in the synthesis of various cardiac glycosides and related bioactive compounds. Its importance lies in its role as a versatile intermediate for pharmaceutical research and development, particularly in the study of Na+/K+-ATPase inhibitors. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable building blocks for drug discovery and advanced synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical starting material or intermediate in the synthesis of novel cardiac glycosides and other therapeutic agents targeting heart conditions.
• Biochemical Research: Used as a reference standard and active compound in pharmacological studies, particularly for investigating Na+/K+-ATPase inhibition and related cellular pathways.
• Natural Product Chemistry: Employed in the isolation, characterization, and semi-synthetic modification of plant-derived cardenolides for structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Acts as a specialized building block for the preparation of complex molecules in medicinal chemistry and custom synthesis projects.
• Reference Standard: Provides a high-purity standard for quality control and analytical method development in laboratories analyzing plant extracts or related pharmaceuticals.

Basic Information

Product Name	Uzarigenin
CAS No.	466-09-1
Molecular Formula	C23H34O4
Molecular Weight	374.52 g/mol
Synonyms	Uzarigenin; (3β,5β,14β)-3,14-Dihydroxy-19-oxocard-20(22)-enolide; 3β,14-Dihydroxy-5β-card-20(22)-enolide; 3β,14-Dihydroxy-5β,14β-card-20(22)-enolide; NSC 17671; Uzarigenine; 19-Oxouzarigenin
EINECS	Contact for details

Quality Control

Our Uzarigenin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.