Description

I-Cholesterol CAS NO 465-54-3 is a high-purity isomer of cholesterol, a fundamental sterol molecule essential for research and development in life sciences. This compound is critical for studying lipid metabolism, membrane biophysics, and as a key intermediate in the synthesis of more complex steroidal compounds. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and diagnostic reagents.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and starting material for the synthesis of steroid-based drugs, hormone analogs, and novel therapeutic agents.
• Biochemical & Nutritional Studies: Used as a precise substrate in enzymatic assays and metabolic pathway studies to investigate cholesterol biosynthesis, absorption, and regulation.
• Liposome & Drug Delivery System Formulation: Acts as a membrane-stabilizing component in the creation of liposomal carriers for targeted drug delivery.
• Diagnostic Reagent Manufacturing: Employed in the production of calibration standards and reagents for clinical diagnostic kits measuring cholesterol and related lipids.
• Academic & Industrial Research: Fundamental tool for basic research in cell biology, biochemistry, and material science related to lipid membranes and sterol function.
• Fine Chemical Synthesis: A valuable chiral building block for the organic synthesis of complex natural products and specialty chemicals.

Basic Information

Product Name	I-Cholesterol
CAS No.	465-54-3
Molecular Formula	C27H46O
Molecular Weight	386.65 g/mol
Synonyms	5α-Cholest-8-en-3β-ol; (3β)-Cholest-8-en-3-ol; Isocholesterol; δ8-Cholesterol; 8-Cholesterol; Cholest-8-en-3β-ol; L-Cholesterol (less common); Allocholesterol (historical)
EINECS	207-364-1

Quality Control

Our I-Cholesterol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for research and industrial use. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.