Description

3Beta,14,16Beta-Trihydroxy-5-Betacard-20(22)-Enolide 16-Acetate is a high-purity, specialized cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. Its precise stereochemistry and functional groups make it an essential building block for developing novel therapeutic agents targeting cardiovascular function. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of cardiac drugs and related biochemical studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex cardiac glycosides and related steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and research tool in studies of cardiac muscle contractility, sodium-potassium ATPase inhibition, and structure-activity relationships (SAR).
• Medicinal Chemistry: Serves as a scaffold for the design and development of new cardioprotective agents and inotropic drugs.
• Analytical Standard: Employed in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical products.

Basic Information

Product Name	3Beta,14,16Beta-Trihydroxy-5-Betacard-20(22)-Enolide 16-Acetate
CAS No.	465-15-6
Molecular Formula	C27H40O8
Molecular Weight	492.61 g/mol
Synonyms	16-Acetylgitoxin; 16-Acetyl Gitoxin; 3β,14,16β-Trihydroxy-5β-card-20(22)-enolide 16-acetate; 16-O-Acetylgitoxin; Gitoxin 16-acetate; 3β,14β,16β-Trihydroxy-5β-card-20(22)-enolide 16-acetate; 16-Acetyl-3β,14,16β-trihydroxy-5β,14β-card-20(22)-enolide
EINECS	Contact for details

Quality Control

Our 3Beta,14,16Beta-Trihydroxy-5-Betacard-20(22)-Enolide 16-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.