Description

3α,11α,14-Trihydroxy-5β-Card-20(22)-Enolide is a high-purity cardenolide steroid derivative, a key intermediate in the synthesis of specialized pharmaceutical compounds. Its precise stereochemistry and functional groups make it a valuable building block for research and development in medicinal chemistry. This compound is essential for manufacturers and research institutions focused on developing and producing novel therapeutic agents, particularly in the cardiovascular and oncology fields.

Application

• Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of bioactive cardenolides and related steroid-based drugs.
• Medicinal Chemistry Research: Used in R&D for structure-activity relationship (SAR) studies to develop new therapeutic compounds with targeted biological activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating the mechanism of action of cardiac glycosides and their interactions with biological targets like Na+/K+-ATPase.
• API Synthesis: A precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) for clinical development.

Basic Information

Product Name	3α,11α,14-Trihydroxy-5β-Card-20(22)-Enolide
CAS No.	465-12-3
Molecular Formula	C₂₃H₃₄O₅
Molecular Weight	390.51 g/mol
Synonyms	3α,11α,14-Trihydroxy-5β-card-20(22)-enolide; 3α,11α,14-Trihydroxy-5β,14β-card-20(22)-enolide; 3-Epi-11α-hydroxygitoxigenin; 3-Epi-11α-hydroxygitoxigenin; 11α-Hydroxy-3-epigitoxigenin; Adonitoxigenin; Adonitoxin Genin; Strophanthidol, 3-epi-
EINECS	Contact for details

Quality Control

Our 3α,11α,14-Trihydroxy-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.