Description

3-(3-(Trifluoromethyl)Phenyl)Propanoyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the trifluoromethylphenyl moiety, which imparts unique electronic and lipophilic properties to target molecules, enhancing their metabolic stability and bioavailability. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to construct complex active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Used in the production of specialty chemicals for electronic displays and organic light-emitting diodes due to its aromatic structure.
• Polymer Modification: Acts as a monomer or chain modifier in the creation of high-performance polymers with specific thermal and chemical resistance.
• Peptide & Protein Chemistry: Employed as an acylating agent for the modification of amino acids and peptides in biochemical research.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex dyes and pigments requiring specific light-fastness and color properties.

Basic Information

Product Name	3-(3-(Trifluoromethyl)Phenyl)Propanoyl Chloride
CAS No.	455-03-8
Molecular Formula	C10H8ClF3O
Molecular Weight	236.62 g/mol
Synonyms	3-[3-(Trifluoromethyl)phenyl]propionyl chloride; 3-(3-Trifluoromethylphenyl)propanoic acid chloride; 3-(3-Trifluoromethylphenyl)propionyl chloride; m-Trifluoromethylhydrocinnamoyl chloride; 3-(m-Trifluoromethylphenyl)propanoyl chloride; β-(3-Trifluoromethylphenyl)propionyl chloride; Hydrocinnamoyl chloride, 3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-(3-(Trifluoromethyl)Phenyl)Propanoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon). This material is hygroscopic (moisture-sensitive) and reacts violently with water, strong bases, and alcohols. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Acid Value	Contact for details
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.