Description

3-(Trifluoromethyl)Phenethyl Alcohol is a versatile fluorinated aromatic alcohol building block, characterized by its phenethyl backbone and a strategically positioned trifluoromethyl group. This molecular architecture provides unique physicochemical properties, making it a valuable intermediate for synthesizing advanced materials and active pharmaceutical ingredients. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate fluorine for enhanced bioactivity and stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies, where the trifluoromethyl group can improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms contribute to increased efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to introduce fluorine into polymer side chains, imparting properties such as oil repellency, chemical resistance, and low surface energy for coatings and specialty plastics.
• Organic Synthesis Building Block: The alcohol functionality allows for further derivatization (e.g., esterification, etherification) to create a library of more complex fluorinated compounds for research and screening.
• Flavor & Fragrance Chemistry: Potential use in synthesizing novel aromatic compounds with unique olfactory profiles, leveraging the distinct electronic effects of the CF3 group.

Basic Information

Product Name	3-(Trifluoromethyl)Phenethyl Alcohol
CAS No.	455-01-6
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	2-[3-(Trifluoromethyl)phenyl]ethanol; 3-(Trifluoromethyl)phenylethanol; m-(Trifluoromethyl)phenethyl Alcohol; 2-(3-Trifluoromethylphenyl)ethan-1-ol; α-Trifluoromethylphenethyl Alcohol; 3-CF3-Phenethyl Alcohol; 3-Trifluoromethylbenzeneethanol; β-(3-Trifluoromethylphenyl)ethanol
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Phenethyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly closed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.