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α-Methyl-3-(Trifluoromethyl)Benzyl Alcohol CAS NO 454-91-1


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CAS No.:454-91-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

α-Methyl-3-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated benzyl alcohol derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoromethyl group, which is highly sought after for modifying the physicochemical properties of target molecules. This compound is essential for research and production chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced metabolic stability and bioavailability.

Application

  • Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
  • Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profile.
  • Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic display and lighting technologies.
  • Advanced Polymer Chemistry: Monomer or modifier for creating specialty polymers with specific thermal, chemical, or surface properties.
  • Organic Synthesis & Catalysis: Valuable reagent in asymmetric synthesis and as a ligand precursor in transition metal catalysis.
  • Flavor & Fragrance Industry: Intermediate for the synthesis of complex aromatic compounds.

Basic Information

Product Name α-Methyl-3-(Trifluoromethyl)Benzyl Alcohol
CAS No. 454-91-1
Molecular Formula C9H9F3O
Molecular Weight 190.16 g/mol
Synonyms α-Methyl-3-(trifluoromethyl)benzyl alcohol; (RS)-1-[3-(Trifluoromethyl)phenyl]ethanol; 1-(3-Trifluoromethylphenyl)ethanol; 3-(Trifluoromethyl)benzeneethanol; 1-(3-(Trifluoromethyl)phenyl)ethan-1-ol; m-(Trifluoromethyl)phenethyl alcohol; α-Methyl-m-(trifluoromethyl)benzyl alcohol
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Quality Control

Our α-Methyl-3-(Trifluoromethyl)Benzyl Alcohol is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee (for enantiopure grades)
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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