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1-(p-Fluorophenyl)Ethanol CAS NO 450-94-2


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CAS No.:450-94-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(p-Fluorophenyl)Ethanol is a versatile fluorinated aromatic alcohol, serving as a critical chiral intermediate and building block in advanced organic synthesis. Its value lies in the unique reactivity of the hydroxyl group and the electronic influence of the para-fluorine substituent, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in neuroactive and anti-inflammatory drug candidates.
  • Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and pesticides where the fluorine atom enhances bioactivity and environmental stability.
  • Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic display materials, improving dielectric anisotropy and stability.
  • Asymmetric Catalysis & Ligand Preparation: Valuable precursor for synthesizing chiral ligands and auxiliaries used in enantioselective catalytic processes.
  • Fine Chemical & Flavor/Fragrance Intermediate: Employed in the multi-step synthesis of complex aromatic compounds for specialty applications.
  • Polymer Modification: Acts as a monomer or chain modifier for introducing fluorinated phenyl groups into polymers to alter physical properties.

Basic Information

Product Name 1-(p-Fluorophenyl)Ethanol
CAS No. 450-94-2
Molecular Formula C8H9FO
Molecular Weight 140.16 g/mol
Synonyms 1-(4-Fluorophenyl)ethanol; (4-Fluorophenyl)methyl carbinol; α-Methyl-4-fluorobenzyl alcohol; p-Fluoro-α-methylbenzyl alcohol; 4-Fluoro-α-methylbenzenemethanol; 1-(4-Fluorophenyl)ethyl alcohol; (±)-1-(4-Fluorophenyl)ethanol
EINECS 207-185-5

Quality Control

Our 1-(p-Fluorophenyl)Ethanol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC/HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Specific Rotation (if chiral) Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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