Description

1-(4-Chlorophenyl)-2,2,2-Trifluoroethanol is a versatile fluorinated aromatic alcohol building block. This compound is valued for its unique structure, which combines a chlorophenyl group with a trifluoroethanol moiety, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated or chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes.
• Specialty Polymer Modifier: Incorporated to impart specific properties like chemical resistance or altered solubility in high-performance polymers.
• Organic Synthesis Reagent: Employed in asymmetric synthesis, chiral resolution, and as a precursor for other complex fluoroorganic compounds in academic and industrial research.

Basic Information

Product Name	1-(4-Chlorophenyl)-2,2,2-Trifluoroethanol
CAS No.	446-66-2
Molecular Formula	C8H6ClF3O
Molecular Weight	210.58 g/mol
Synonyms	4-Chloro-α-(trifluoromethyl)benzyl Alcohol; (4-Chlorophenyl)trifluoroethanol; α,α,α-Trifluoro-4-chlorobenzyl Alcohol; 2,2,2-Trifluoro-1-(4-chlorophenyl)ethanol; 1-(p-Chlorophenyl)-2,2,2-trifluoroethanol; p-Chloro-α,α,α-trifluoromethylbenzyl Alcohol; 4-Chloro-α-(trifluoromethyl)benzenemethanol
EINECS	207-179-9

Quality Control

Our production of 1-(4-Chlorophenyl)-2,2,2-Trifluoroethanol adheres to stringent quality management protocols. Each batch is thoroughly analyzed using advanced techniques including HPLC, GC, and NMR to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.