Description

1,2-Benzenedicarbonyl Difluoride (9Ci) is a highly reactive aromatic diacyl fluoride derivative, serving as a critical fluorinating and acylating agent in advanced organic synthesis. Its value lies in enabling efficient, high-yield reactions for constructing complex molecular architectures, particularly where traditional acid chlorides are unsuitable. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, where it is used to introduce phthaloyl groups and create novel fluorinated intermediates. The product is supplied with CAS NO 445-69-2.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring fluorinated phthalimide structures.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of high-performance polyimides, polyamides, and other engineering plastics with enhanced thermal and chemical resistance.
• Ligand and Catalyst Preparation: Employed in the fabrication of specialized ligands for metal-organic frameworks (MOFs) and organometallic catalysts.
• Fluorination Reagent: Serves as a source of fluorine atoms in nucleophilic and electrophilic fluorination reactions to create other valuable fluoroorganic compounds.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	1,2-Benzenedicarbonyl Difluoride (9Ci)
CAS No.	445-69-2
Molecular Formula	C8H2F2O2
Molecular Weight	168.10 g/mol
Synonyms	Phthaloyl Difluoride; 1,2-Benzenedicarboxylic Acid Difluoride; Phthalic Acid Difluoride; Difluorophthalic Anhydride; o-Phthaloyl Difluoride; Benzene-1,2-dicarbonyl Difluoride; Isophthaloyl Difluoride Isomer; Terephthaloyl Difluoride Isomer
EINECS	207-167-5

Quality Control

Our 1,2-Benzenedicarbonyl Difluoride is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including assay by titration, impurity profiling via GC/HPLC, and identity confirmation by FT-IR and NMR spectroscopy. A detailed Certificate of Analysis (COA) documenting purity, physical properties, and safety data is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (Titration)	≥ 98.0 %
Purity (HPLC)	≥ 97.0 %
Melting Point	Contact for details
Water Content (KF)	≤ 0.5 %
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.