Description

1-(2-Fluorophenyl)Ethanol is a versatile fluorinated aromatic alcohol, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom and the benzylic alcohol functional group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides where the fluorophenyl moiety enhances biological activity and stability.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate for manufacturing dyes, flavors, fragrances, and liquid crystals.
• Academic & R&D: Valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and stereoselective transformations.
• Material Science: Monomer or modifier in the synthesis of specialty polymers with tailored optical or electronic properties.

Basic Information

Product Name	1-(2-Fluorophenyl)Ethanol
CAS No.	445-26-1
Molecular Formula	C8H9FO
Molecular Weight	140.16 g/mol
Synonyms	2-Fluorobenzyl Alcohol; (2-Fluorophenyl)methanol; α-Fluoro-o-xylene-α-ol; 2-Fluorobenzyl Alcohol; o-Fluorobenzyl Alcohol; 1-(2-Fluorophenyl)methanol; 2-Fluorophenylmethanol; Benzenemethanol, 2-fluoro-
EINECS	207-162-3

Quality Control

Our 1-(2-Fluorophenyl)Ethanol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC/GC purity, chiral purity (enantiomeric excess), and identity confirmation (IR, NMR). A detailed Certificate of Analysis (COA) is supplied with each shipment, and we support compliance with REACH, FDA, and cGMP guidelines for relevant applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Chiral Purity (ee)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.