Description

2-Phenyl-1,1,1-Trifluoropropan-2-Ol is a versatile fluorinated tertiary alcohol building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of a robust phenyl group and a highly electron-withdrawing trifluoromethyl group, which imparts desirable properties to target molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly those requiring enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the trifluoromethyl group improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Incorporated into specialty polymers and liquid crystals to modify thermal and optical properties.
• Fluorine Chemistry Research: An essential reagent for studying the introduction and effects of fluorinated motifs in organic molecules.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value fluorinated compounds.

Basic Information

Product Name	2-Phenyl-1,1,1-Trifluoropropan-2-Ol
CAS No.	426-54-0
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	α,α,α-Trifluoro-2-phenylethanol; 1,1,1-Trifluoro-2-phenylethan-2-ol; 2-Phenyl-2-trifluoromethyl ethanol; (2,2,2-Trifluoro-1-hydroxy-1-phenylethane); α-(Trifluoromethyl)benzyl alcohol; Benzhydrol, α-(trifluoromethyl)-; Hexafluorocumyl alcohol (related); TFMPA (abbreviation)
EINECS	207-049-9

Quality Control

Every batch of 2-Phenyl-1,1,1-Trifluoropropan-2-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.