Acetyl Bromide, 2-Chloro-2,2-Difluoro- CAS NO 421-45-4

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CAS No.:421-45-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Acetyl Bromide, 2-Chloro-2,2-Difluoro- is a highly reactive organofluorine building block, specifically a halogenated acetyl bromide derivative. This compound is valued for its ability to introduce the difluoromethyl group and serve as an acylating agent in complex synthetic pathways. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing difluoromethyl ether or difluoromethyl ketone motifs.
Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the difluoromethyl group enhances biological activity and metabolic stability.
Material Science: Employed in the research and development of specialty polymers and liquid crystals that require specific fluorine-containing segments.
Organic Synthesis Reagent: Acts as a versatile reagent for acylations and as a precursor for other organofluorine compounds in academic and industrial R&D laboratories.
Fluorine Chemistry Research: Essential for methodological studies and the exploration of new fluorination reactions and mechanisms.

Basic Information


Product Name	Acetyl Bromide, 2-Chloro-2,2-Difluoro-
CAS No.	421-45-4
Molecular Formula	C2HClF2BrO
Molecular Weight	179.38 g/mol
Synonyms	2-Chloro-2,2-difluoroacetyl Bromide; Chlorodifluoroacetyl Bromide; Difluorochloroacetyl Bromide; α-Chloro-α,α-difluoroacetyl Bromide; Bromocarbonylchlorodifluoromethane; 2,2-Difluoro-2-chloroacetyl Bromide; Acetyl Bromide, 2-chloro-2,2-difluoro- (8CI)
EINECS	Contact for details

Quality Control

Our Acetyl Bromide, 2-Chloro-2,2-Difluoro- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including assay by GC/HPLC and impurity profiling, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and safety parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.