Description

4-(Fluorosulfonyl)Benzoyl Chloride is a highly reactive and versatile aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a benzoyl chloride and a fluorosulfonyl group, makes it an indispensable reagent for introducing functionalized benzoate moieties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for creating novel sulfonamide and ester-based compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing sulfonamide or benzoate ester functional groups.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorosulfonylbenzoyl unit imparts specific biological activity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing high-performance polymers, liquid crystals, and specialty coatings.
• Chemical Research & Development: A valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye & Pigment Manufacturing: Intermediate in the production of specialized dyes and optical brighteners.
• Ligand & Catalyst Design: Used to synthesize complex ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	4-(Fluorososyl)Benzoyl Chloride
CAS No.	402-55-1
Molecular Formula	C7H4ClFO3S
Molecular Weight	222.62 g/mol
Synonyms	p-(Fluorosulfonyl)benzoyl chloride; 4-Fluorosulfonylbenzoyl chloride; Benzoic acid, 4-(fluorosulfonyl)-, chloride; 4-Fluorobenzenesulfonyl chloride; 4-Carboxybenzenesulfonyl fluoride chloride; α-Oxo-4-(fluorosulfonyl)benzeneacetyl chloride; (4-Fluorosulfonylphenyl)carbonyl chloride
EINECS	206-947-4

Quality Control

Our 4-(Fluorosulfonyl)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.