Description

1-(2-Bromophenyl)-2,2,2-trifluoroethanol is a high-value fluorinated aromatic building block, distinguished by its unique combination of a bromine substituent and a trifluoroethanol moiety. This compound is critical for introducing both halogen and fluorinated alcohol functionalities into target molecules, enabling precise control over molecular properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and as a key intermediate in the synthesis of more complex active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Acts as a key intermediate for creating fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in the preparation of specialized chiral ligands and organocatalysts for asymmetric synthesis.
• Advanced Polymer Chemistry: Incorporated into monomers for synthesizing high-performance, fluorinated polymers with unique surface properties and chemical resistance.
• Chemical Research & Development: A versatile reagent for exploratory synthesis in academic and industrial R&D settings to create new chemical entities.

Basic Information

Product Name	1-(2-Bromophenyl)-2,2,2-Trifluoroethanol
CAS No.	394203-55-5
Molecular Formula	C8H6BrF3O
Molecular Weight	255.03 g/mol
Synonyms	2-Bromo-α-(trifluoromethyl)benzyl alcohol; (2-Bromophenyl)(trifluoromethyl)methanol; 1-(2-Bromophenyl)-2,2,2-trifluoroethan-1-ol; α-(Trifluoromethyl)-2-bromobenzyl alcohol; 2-Bromo-α,α,α-trifluorotoluene-α-ol; o-Bromo-α-(trifluoromethyl)benzyl alcohol; 2-Bromobenzotrifluoromethyl alcohol
EINECS	Contact for details

Quality Control

Our 1-(2-Bromophenyl)-2,2,2-trifluoroethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data, including HPLC purity, NMR confirmation, and residual solvent analysis. Our quality commitment ensures the material meets the stringent requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.