Description

2,5-Diisothiocyanato-Benzenesulphonic Acid 2 H2O is a specialized bifunctional organic compound containing both isothiocyanate and sulfonic acid groups, making it a valuable building block for chemical synthesis. This compound is particularly significant for its role as a versatile linker and derivatization agent in advanced material science and life sciences research. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel polymers, coatings, and bioactive conjugates.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly as a bifunctional linker for antibody-drug conjugates (ADCs) and other targeted therapies.
• Polymer Chemistry: Serves as a key monomer or cross-linking agent for producing specialty polymers with unique thermal or chemical resistance properties.
• Bioconjugation & Protein Labeling: The isothiocyanate groups react with amine functionalities, making it effective for fluorescent labeling, immobilizing proteins on surfaces, or modifying biomolecules.
• Agrochemical Synthesis: Employed in the research and development of new pesticides and herbicides due to its reactive sites that can be tailored for specific biological activity.
• Material Science Research: Utilized in the development of advanced materials such as metal-organic frameworks (MOFs), functionalized nanoparticles, and conductive polymers.
• Analytical Chemistry: Acts as a derivatization agent in chromatography to enhance the detection or separation of specific analytes.

Basic Information

Item	Detail
Product Name	2,5-Diisothiocyanato-Benzenesulphonic Acid 2 H2O
CAS No.	384819-92-5
Molecular Formula	C8H6N2O5S3 • 2H2O
Molecular Weight	328.35 g/mol (Anhydrous basis: 292.34 g/mol)
Synonyms	2,5-Diisothiocyanatobenzenesulfonic Acid Dihydrate; 1,4-Diisothiocyanato-2-sulfobenzene Dihydrate; Benzenesulfonic acid, 2,5-diisothiocyanato-, dihydrate; 2,5-Diisothiocyanato-1-sulfobenzene; BDBSA; 2,5-Diisothiocyanatobenzene-1-sulfonic acid
EINECS	Contact for details

Quality Control

Our 2,5-Diisothiocyanato-Benzenesulphonic Acid 2 H2O is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	9.0 - 12.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.