Description

3'-Azido-3'-Deoxy-N6,N6-Dimethyladenosine is a chemically modified nucleoside analog, a key intermediate in the synthesis of bioactive molecules and oligonucleotides. This compound is valued for its unique azido functionality, which enables efficient "click chemistry" reactions for bioconjugation and labeling applications. It is primarily utilized by researchers and manufacturers in pharmaceutical development, life sciences, and chemical synthesis for creating novel probes and therapeutic candidates.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Bioconjugation & Labeling: The azido group facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC) for attaching fluorescent dyes, biotin, or other molecules to biomolecules.
• Oligonucleotide Synthesis: Used in the preparation of modified DNA/RNA strands for research, diagnostics, and therapeutic applications like antisense oligonucleotides.
• Chemical Biology Probes: Enables the creation of activity-based probes to study enzyme function and metabolic pathways in cells.
• Glycobiology Research: Serves as a precursor for synthesizing modified sugars and nucleosides to investigate glycosylation processes.
• Material Science: Can be incorporated into polymers or surfaces to create functionalized materials with specific biological activity.

Basic Information

Product Name	3'-Azido-3'-Deoxy-N6,N6-Dimethyladenosine
CAS No.	384334-64-9
Molecular Formula	C12H16N8O3
Molecular Weight	320.31 g/mol
Synonyms	3'-Azido-3'-deoxy-N6,N6-dimethyladenosine; 3'-Azido-N6,N6-dimethyl-3'-deoxyadenosine; 3'-Azido-3'-deoxy-N6,N6-dimethyladenosine; 9-[(3-Azido-3-deoxy-β-D-ribofuranosyl)-N6,N6-dimethyladenine]; N6,N6-Dimethyl-3'-azido-3'-deoxyadenosine; 3'-Azido-N6,N6-dimethyladenosine; 3'-N3-N6,N6-Dimethyl-3'-deoxyadenosine
EINECS	Contact for details

Quality Control

Our 3'-Azido-3'-Deoxy-N6,N6-Dimethyladenosine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.