Description

6-Methyl-3-(β-D-2-Deoxyfuranosyl)Pyrrolo[2,3-D]Pyrimidin-2-One CAS NO 382137-74-8 is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. Its core value lies in its role as a key synthetic intermediate for novel antiviral and anticancer therapeutics, enabling the creation of targeted, high-efficacy drug candidates. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies focused on nucleoside-based medicinal chemistry and prodrug development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside analog drugs targeting viral infections and oncology.
• Antiviral Drug Development: Used in R&D for creating next-generation antiviral agents, particularly against DNA viruses.
• Anticancer Prodrug Synthesis: Serves as a precursor in the development of targeted chemotherapeutic prodrugs designed for selective activation.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties.
• Biochemical Tool Compound: Employed in enzymatic studies to investigate nucleoside metabolism and related biological pathways.
• Contract Manufacturing: Supplied to CDMOs for use in custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	6-Methyl-3-(β-D-2-Deoxyfuranosyl)Pyrrolo[2,3-D]Pyrimidin-2-One
CAS No.	382137-74-8
Molecular Formula	C12H15N3O4
Molecular Weight	265.26 g/mol
Synonyms	6-Methyl-3-(2-deoxy-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2(3H)-one; 6-Methyl-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3H-pyrrolo[2,3-d]pyrimidin-2-one; 2'-Deoxy-6-methylpyrrolo[2,3-d]pyrimidin-2-one nucleoside; 6-Methyl-3-(2-deoxy-β-D-ribofuranosyl)-3H-pyrrolo[2,3-d]pyrimidin-2-one; 382137-74-8; Pyrrolo[2,3-d]pyrimidin-2-one nucleoside derivative
EINECS	Contact for details

Quality Control

Our 6-Methyl-3-(β-D-2-Deoxyfuranosyl)Pyrrolo[2,3-D]Pyrimidin-2-One is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All batches undergo comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.