Description

5-(2-Methyl-4-Nitrophenyl)Furan-2-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life sciences industries for constructing novel heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing furan and nitrophenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive acid chloride functionality.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers and advanced organic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex organic dyes and pigments due to the presence of the nitro and furan groups.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including coupling reactions and heterocycle formation.
• Ligand and Catalyst Development: Used to create novel chelating ligands for metal catalysts in asymmetric synthesis.

Basic Information

Product Name	5-(2-Methyl-4-Nitrophenyl)Furan-2-Carbonyl Chloride
CAS No.	381178-60-5
Molecular Formula	C12H8ClNO4
Molecular Weight	265.65 g/mol
Synonyms	2-Furoyl chloride, 5-(2-methyl-4-nitrophenyl)-; 5-(2-Methyl-4-nitrophenyl)-2-furancarbonyl chloride; 5-(2-Methyl-4-nitrophenyl)furan-2-carbonyl chloride; 2-Methyl-4-nitrophenylfuran-2-carbonyl chloride; (5-(2-Methyl-4-nitrophenyl)furan-2-yl)methanoyl chloride
EINECS	Contact for details

Quality Control

Our 5-(2-Methyl-4-Nitrophenyl)Furan-2-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.