Description

Bosutinib is a potent and selective small-molecule tyrosine kinase inhibitor targeting the Bcr-Abl and Src family kinases. This compound is of significant commercial and research interest as a key active pharmaceutical ingredient (API) in the development of targeted cancer therapies. It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in oncology drug development and production.

Application

• Primary Active Pharmaceutical Ingredient (API) for the formulation of targeted cancer therapeutics.
• Critical raw material in pharmaceutical R&D for studying Bcr-Abl and Src kinase inhibition pathways.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Intermediate for the synthesis of more complex molecular entities in advanced medicinal chemistry.
• Biochemical research tool for investigating cellular signaling mechanisms in oncology.

Basic Information

Product Name	Bosutinib
CAS No.	380843-75-4
Molecular Formula	C₂₆H₂₉Cl₂N₅O₃
Molecular Weight	530.44 g/mol
Synonyms	SKI-606; 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile; Bosulif (Trade Name); UNII-5018V4AEZ0
EINECS	Contact for details

Quality Control

Our Bosutinib is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.