Description

4-(Oxoboronyl)Benzoyl Chloride is a specialized organoboron reagent featuring a highly reactive acid chloride functional group. This compound is a critical building block in modern synthetic chemistry, enabling the precise introduction of the 4-boronylbenzoyl moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as cross-coupling reactions and the synthesis of complex bioactive compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for boron-containing drug candidates.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as an electrophilic coupling partner with organoboronic acids/esters to form biaryl and other conjugated systems.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that incorporate boron for enhanced activity.
• Material Science & OLED Development: Building block for organic semiconductors, liquid crystals, and electron-transport materials in display technologies.
• Peptide & Protein Modification: Facilitates the site-specific labeling or functionalization of biomolecules via reaction with amine groups.
• Polymer Chemistry: Monomer for synthesizing specialty polymers with unique thermal or optical properties.
• Chemical Biology Probes: Used to develop activity-based probes and inhibitors for studying enzyme function.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploring new chemical spaces in organic synthesis.

Basic Information

Product Name	4-(Oxoboronyl)Benzoyl Chloride
CAS No.	380430-63-7
Molecular Formula	C7H4BBrClO2 (Note: Based on common structure; contact for confirmation)
Molecular Weight	Contact for details
Synonyms	4-Carboxybenzene boronic acid chloride; 4-Boronobenzoyl chloride; (4-Chlorocarbonylphenyl)boronic acid; p-Boronobenzoyl chloride; 4-(Dihydroxyboryl)benzoyl chloride; B-(4-Chlorocarbonylphenyl)boronic acid; 4-Boronylbenzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-(Oxoboronyl)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.