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3-(2,4,6-Trifluoro-Phenyl)-Propan-1-Ol CAS NO 377084-10-1
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CAS No.:377084-10-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-(2,4,6-Trifluoro-Phenyl)-Propan-1-Ol is a high-purity fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a propanol chain attached to a symmetrically trifluorinated phenyl ring, makes it a valuable intermediate for creating compounds with tailored electronic and physical properties. This product is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to introduce fluorinated motifs that can enhance metabolic stability, bioavailability, and lipophilicity in active ingredients.
Application
- Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
- Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
- Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials, contributing to improved performance and stability.
- Polymer & Specialty Chemical Modifier: Incorporated into polymer chains or specialty chemicals to impart desirable characteristics such as chemical resistance, low surface energy, or altered solubility.
- Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Heck) to construct complex, fluorinated biaryl structures for material science and medicinal chemistry.
- Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and fluorine chemistry.
Basic Information
| Item | Detail |
|---|---|
| Product Name | 3-(2,4,6-Trifluoro-Phenyl)-Propan-1-Ol |
| CAS No. | 377084-10-1 |
| Molecular Formula | C9H9F3O |
| Molecular Weight | 190.16 g/mol |
| Synonyms | 3-(2,4,6-Trifluorophenyl)propan-1-ol; 3-(2,4,6-Trifluorophenyl)-1-propanol; 2,4,6-Trifluoro-β-hydroxypropylbenzene; 1-Propanol, 3-(2,4,6-trifluorophenyl)-; 377084-10-1; 3-(Perfluorophenyl)propanol (common name for the substitution pattern); β-(2,4,6-Trifluorophenyl)propyl alcohol |
| EINECS | Contact for details |
Quality Control
Every batch of 3-(2,4,6-Trifluoro-Phenyl)-Propan-1-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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