Description

2'-C-Methylinosine is a chemically modified nucleoside analog that serves as a critical building block and intermediate in advanced pharmaceutical research and development. Its unique structure, featuring a methyl group at the 2'-carbon position of the ribose ring, makes it a valuable precursor for the synthesis of novel antiviral and anticancer nucleotide prodrugs. This high-purity intermediate is essential for research institutions and pharmaceutical companies focused on developing next-generation therapeutics targeting RNA viruses and specific cellular pathways.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of nucleotide analogs and prodrugs with antiviral or anticancer activity.
• Antiviral Drug Research: Used in the development of therapeutics targeting hepatitis C virus (HCV), dengue virus, and other RNA viruses.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to understand polymerase mechanisms and nucleotide metabolism.
• Prodrug Synthesis: A crucial precursor for creating masked nucleotide forms designed for improved cellular uptake and bioavailability.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleoside-based drug candidates.

Basic Information

Product Name	2'-C-Methylinosine
CAS No.	374750-32-0
Molecular Formula	C11H14N4O5
Molecular Weight	282.25 g/mol
Synonyms	2'-C-Methylinosine; 2'-Methylinosine; 9-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-3H-purin-6-one; 2'-C-Methyl-9-β-D-ribofuranosylhypoxanthine; Inosine, 2'-C-methyl-; 2'-Methyl-9-β-D-ribofuranosylhypoxanthine
EINECS	Contact for details

Quality Control

Our 2'-C-Methylinosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥99.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.