Description

3-Bromo-2-Fluorobenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual halogen functionality, which enables precise and versatile derivatization for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality raw materials for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzoyl moiety.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromo-fluoro substitution pattern imparts specific biological activity.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating complex organic molecules used in electronic displays and optoelectronic devices.
• Polymer & Resin Modification: Employed to introduce functional groups into polymer chains, altering material properties like solubility, thermal stability, or reactivity.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions (e.g., Suzuki, Heck) to form biaryl structures.
• Peptide Mimetics & Bio-conjugation: Useful for acylating amines in the creation of peptide analogs or for labeling biomolecules.

Basic Information

Product Name	3-Bromo-2-Fluorobenzoyl Chloride
CAS No.	374554-41-3
Molecular Formula	C7H3BrClFO
Molecular Weight	237.45 g/mol
Synonyms	2-Fluoro-3-bromobenzoyl chloride; 3-Bromo-2-fluorobenzoic acid chloride; Benzoic acid, 3-bromo-2-fluoro-, chloride; 3-Bromo-2-fluorobenzoyl chloride; (3-Bromo-2-fluorophenyl)(chloro)methanone
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluorobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.