Description

1H-Pyrrole-2-Carbonyl Chloride, 5-Phenyl- (9Ci) is a specialized heterocyclic building block and key acyl chloride intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel pyrrole-containing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides that incorporate the pyrrole moiety for enhanced biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of conductive polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeled compounds for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1H-Pyrrole-2-Carbonyl Chloride, 5-Phenyl- (9Ci)
CAS No.	368210-50-8
Molecular Formula	C11H8ClNO
Molecular Weight	205.64 g/mol
Synonyms	5-Phenyl-1H-pyrrole-2-carbonyl chloride; 5-Phenyl-2-pyrrolecarbonyl chloride; 2-Carbonyl chloride-5-phenylpyrrole; 5-Phenylpyrrole-2-carboxylic acid chloride; 1H-Pyrrole-2-carbonyl chloride, 5-phenyl-; 368210-50-8; 5-Phenyl-1H-pyrrole-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2-Carbonyl Chloride, 5-Phenyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.