Description

Bufa-20,22-Dienolide, 1,3,14-Trihydroxy-, (1β,3β,5β)- is a high-purity, specialized steroidal compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of bioactive molecules with potential therapeutic applications. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related steroid-based products.
• Biochemical Research: Employed in academic and industrial research to study steroid receptor interactions, metabolic pathways, and biological activity.
• Process Development: Serves as a starting material or intermediate in scaling up synthetic routes for complex steroid molecules.
• Library Synthesis: Utilized in combinatorial chemistry to create diverse arrays of compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	Bufa-20,22-Dienolide, 1,3,14-Trihydroxy-, (1β,3β,5β)-
CAS No.	366004-27-5
Molecular Formula	C24H34O5
Molecular Weight	402.53 g/mol
Synonyms	1β,3β,5β-Bufa-20,22-dienolide-1,3,14-triol; (1β,3β,5β)-1,3,14-Trihydroxybufa-20,22-dienolide; Bufa-20,22-dienolide-1,3,14-triol; 366004-27-5; Bufadienolide derivative; Steroidal lactone intermediate
EINECS	Contact for details

Quality Control

Our Bufa-20,22-Dienolide, 1,3,14-Trihydroxy-, (1β,3β,5β)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.