Description

(1S,3R,4R)-Ethyl 3-Azido-4-Hydroxycyclohexanecarboxylate is a high-purity, stereochemically defined chiral building block of significant synthetic value. This compound is essential for the development of novel pharmaceuticals and complex organic molecules, serving as a key intermediate in advanced synthetic routes. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) and the construction of complex molecular scaffolds.
• Process Chemistry: Serves as a critical intermediate in the development and scale-up of efficient synthetic manufacturing processes.
• Organic Synthesis: Utilized in click chemistry reactions via its azido functionality and for introducing stereochemical complexity in target molecules.
• Agrochemical Research: Potential intermediate in the development of new, stereoselective crop protection agents.

Basic Information

Product Name	(1S,3R,4R)-Ethyl 3-Azido-4-Hydroxycyclohexanecarboxylate
CAS No.	365997-32-6
Molecular Formula	C9H15N3O3
Molecular Weight	213.23 g/mol
Synonyms	Ethyl (1S,3R,4R)-3-azido-4-hydroxycyclohexanecarboxylate; (1S,3R,4R)-3-Azido-4-hydroxycyclohexanecarboxylic Acid Ethyl Ester; trans-Ethyl 3-azido-4-hydroxycyclohexanecarboxylate; 3-Azido-4-hydroxycyclohexanecarboxylic acid ethyl ester, (1S,3R,4R)-; Cyclohexanecarboxylic acid, 3-azido-4-hydroxy-, ethyl ester, (1S,3R,4R)-; AZD-9291 intermediate derivative
EINECS	Contact for details

Quality Control

Our (1S,3R,4R)-Ethyl 3-Azido-4-Hydroxycyclohexanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.