Description

Diethyl 3,5-Dibromobenzylphosphonate is a high-purity organophosphorus compound, specifically a benzylphosphonate derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in pharmaceutical and agrochemical research and development. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those requiring brominated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Precursor: Serves as a precursor for phosphonate-based ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of novel organic materials, including polymers and liquid crystals with specific electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Scale-up and Process Chemistry: Suitable for process optimization and kilogram-scale production under current Good Manufacturing Practice (cGMP) guidelines for pharmaceutical applications.

Basic Information

Product Name	Diethyl 3,5-Dibromobenzylphosphonate
CAS No.	363622-48-4
Molecular Formula	C11H15Br2O3P
Molecular Weight	394.02 g/mol
Synonyms	Diethyl (3,5-dibromobenzyl)phosphonate; (3,5-Dibromobenzyl)phosphonic Acid Diethyl Ester; Phosphonic Acid, P-[(3,5-Dibromophenyl)methyl]-, Diethyl Ester; Diethyl (3,5-Dibromophenylmethyl)phosphonate; Diethyl P-[(3,5-Dibromophenyl)methyl]phosphonate; 3,5-Dibromobenzylphosphonic Acid Diethyl Ester; Benzylphosphonic Acid, 3,5-Dibromo-, Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl 3,5-Dibromobenzylphosphonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of our global customer base, with specifications that can be aligned with cGMP, ICH Q7 guidelines, and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.