Description

2,3-Difluorophenyl Isothiocyanate is a versatile and reactive organofluorine building block essential for advanced chemical synthesis. This compound is particularly valued for its ability to introduce the thiourea pharmacophore into target molecules, enabling the development of compounds with enhanced biological activity and specific binding properties. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to innovate within fluorine chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging fluorine's properties for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of functional polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology Probes: Useful for modifying peptides, proteins, and other biomolecules to study biological pathways and interactions.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and academic labs exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	2,3-Difluorophenyl Isothiocyanate
CAS No.	363179-57-1
Molecular Formula	C7H3F2NS
Molecular Weight	171.17 g/mol
Synonyms	2,3-Difluorophenyl isothiocyanate; 1,2-Difluoro-3-isothiocyanatobenzene; Isothiocyanic Acid 2,3-Difluorophenyl Ester; 2,3-Difluorobenzene Isothiocyanate; 2,3-Difluorophenyl Mustard Oil; (2,3-Difluorophenyl)isothiocyanate
EINECS	Contact for details

Quality Control

Our 2,3-Difluorophenyl Isothiocyanate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.