Description

Benzene, 1-Chloro-4-Fluoro-2-Isothiocyanato- (9Ci) is a specialized aromatic building block featuring a reactive isothiocyanate group, making it a valuable intermediate for constructing complex molecular architectures. Its unique combination of halogen substituents and the versatile isothiocyanate functionality is critical for introducing sulfur-containing motifs in advanced synthesis. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for creating thiourea and heterocyclic scaffolds with potential biological activity.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the isothiocyanate group can act as a reactive handle for further derivatization.
• Material Science: Employed in the synthesis of functionalized polymers and advanced materials requiring specific aromatic and sulfur-based components.
• Chemical Biology: Acts as a labeling or cross-linking agent in probe development due to the electrophilic nature of the isothiocyanate group, which reacts with amines.
• Organic Synthesis: A versatile building block for constructing complex molecules in academic and industrial research settings, enabling the introduction of both halogen and sulfur functionalities.

Basic Information

Product Name	Benzene, 1-Chloro-4-Fluoro-2-Isothiocyanato- (9Ci)
CAS No.	362690-57-1
Molecular Formula	C7H3ClFNS
Molecular Weight	187.62 g/mol
Synonyms	1-Chloro-4-fluoro-2-isothiocyanatobenzene; 2-Chloro-5-fluorophenyl isothiocyanate; 2-Isothiocyanato-1-chloro-4-fluorobenzene; 5-Fluoro-2-chlorophenyl isothiocyanate; Benzene, 1-chloro-4-fluoro-2-isothiocyanato-; 2-Chloro-5-fluoro-1-isothiocyanatobenzene; (2-Chloro-5-fluorophenyl) isothiocyanate
EINECS	Contact for details

Quality Control

Our Benzene, 1-Chloro-4-Fluoro-2-Isothiocyanato- (9Ci) is produced under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.