Description

Benzene, 1-Bromo-2-Fluoro-4-Isothiocyanato- (9Ci) is a specialized halogenated benzene derivative that serves as a versatile and high-value synthetic intermediate. Its unique structure, incorporating bromo, fluoro, and isothiocyanato functional groups, makes it a critical building block for constructing complex molecules in advanced research and development. This compound is primarily utilized by pharmaceutical and agrochemical researchers for the synthesis of novel active ingredients and by material scientists exploring new functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used to develop new pesticides and herbicides, where the introduction of fluorine and sulfur-containing moieties can enhance biological activity and environmental stability.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands and chelating agents used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the development of advanced polymers and liquid crystals, where its aromatic core and functional groups can impart specific electronic or structural properties.
• Chemical Biology Probe Development: The reactive isothiocyanato group makes it useful for synthesizing affinity-based probes for studying protein function and interactions.

Basic Information

Product Name	Benzene, 1-Bromo-2-Fluoro-4-Isothiocyanato- (9Ci)
CAS No.	362690-56-0
Molecular Formula	C7H3BrFNS
Molecular Weight	232.07 g/mol
Synonyms	1-Bromo-2-fluoro-4-isothiocyanatobenzene; 4-Bromo-3-fluorophenyl isothiocyanate; 2-Fluoro-4-isothiocyanato-1-bromobenzene; 3-Fluoro-4-bromophenyl isothiocyanate; (3-Fluoro-4-bromophenyl) isothiocyanate; Benzene, 1-bromo-2-fluoro-4-isothiocyanato-; 362690-56-0; 4-Bromo-3-fluoro-1-isothiocyanatobenzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-Bromo-2-Fluoro-4-Isothiocyanato- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.