Description

Benzene, 1,2,4-Trifluoro-3-Isothiocyanato- (9Ci) is a specialized fluorinated aromatic building block containing a reactive isothiocyanate group. This compound is valued for its unique molecular architecture, enabling the synthesis of complex heterocyclic systems and advanced materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for advanced polymers and liquid crystals with tailored electronic and optical properties.
• Chemical Synthesis: Acts as a versatile reagent for introducing the isothiocyanate moiety into complex molecules for further derivatization.
• Bioconjugation: Potential use in labeling biomolecules due to the reactivity of the isothiocyanate group with amines.

Basic Information

Product Name	Benzene, 1,2,4-Trifluoro-3-Isothiocyanato- (9Ci)
CAS No.	362690-54-8
Molecular Formula	C7H2F3NS
Molecular Weight	197.16 g/mol
Synonyms	3-Isothiocyanato-1,2,4-trifluorobenzene; 1,2,4-Trifluoro-3-isothiocyanatobenzene; 1,2,4-Trifluoro-3-isothiocyanato-Benzene; NSC 405124; 362690-54-8; 1,2,4-Trifluoro-3-isothiocyanato benzene; Benzene, 1,2,4-trifluoro-3-isothiocyanato-
EINECS	Contact for details

Quality Control

Our Benzene, 1,2,4-Trifluoro-3-Isothiocyanato- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under an inert atmosphere after opening to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.