Description

Benzene, 1,2,3-Trifluoro-5-Isothiocyanato- (9Ci) is a specialized fluorinated aromatic building block containing a reactive isothiocyanate functional group. This compound is valued for its ability to introduce both fluorine atoms and a versatile chemical handle into target molecules, enabling the synthesis of novel materials and active compounds. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for advanced R&D and scale-up projects. CAS number 362690-52-6.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where fluorine atoms can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for advanced polymers, liquid crystals, or organic electronic materials requiring specific fluorine substitution patterns.
• Chemical Biology Probes: The reactive isothiocyanate group allows for covalent labeling of proteins or other biomolecules, useful in probe and diagnostic agent development.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs for the production of complex, customer-specific fluorinated compounds.

Basic Information

Product Name	Benzene, 1,2,3-Trifluoro-5-Isothiocyanato- (9Ci)
CAS No.	362690-52-6
Molecular Formula	C7H2F3NS
Molecular Weight	189.16 g/mol
Synonyms	1,2,3-Trifluoro-5-isothiocyanatobenzene; 5-Isothiocyanato-1,2,3-trifluorobenzene; 2,3,4-Trifluorophenyl isothiocyanate; 1,2,3-Trifluoro-5-isothiocyanato-Benzene; Benzene, 1,2,3-trifluoro-5-isothiocyanato-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.