Description

Isoguanosine Hydrate CAS NO 359436-55-8 is a purine nucleoside analog, a key building block in nucleic acid chemistry and pharmaceutical research. This compound is valued for its role as a precursor in the synthesis of modified nucleosides and nucleotides, which are critical for developing antiviral agents, anticancer drugs, and tools for molecular biology. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on advanced therapeutic and diagnostic applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleic acid metabolism and related pathways.
• Probe and Diagnostic Development: Acts as a starting material for creating labeled nucleosides used in diagnostic assays and imaging probes.
• Antisense Oligonucleotide Synthesis: Employed in the preparation of modified oligonucleotides for therapeutic and research applications.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Isoguanosine Hydrate
CAS No.	359436-55-8
Molecular Formula	C10H13N5O5 • xH2O
Molecular Weight	283.24 g/mol (Anhydrous basis)
Synonyms	9-β-D-Ribofuranosylisoguanine Hydrate; 6-Amino-9-β-D-ribofuranosyl-1H-purin-2(3H)-one Hydrate; Iso-G Hydrate; 2-Hydroxyadenosine Hydrate; 6-Amino-2-hydroxy-9-β-D-ribofuranosylpurine Hydrate; 9H-Purin-2-ol, 6-amino-9-β-D-ribofuranosyl-, Hydrate
EINECS	Contact for details

Quality Control

Our Isoguanosine Hydrate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and water content, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.