Description

Benzoyl Chloride,2,3,4-Trihydroxy- CAS NO 355374-15-1 is a specialized benzoyl chloride derivative featuring a trihydroxy-substituted aromatic ring, making it a valuable multifunctional synthetic intermediate. This compound is critical for introducing the benzoyl protecting group in complex organic syntheses, particularly where subsequent deprotection under mild conditions is required. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the production of advanced active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, particularly in the development of glycosidase inhibitors and other bioactive compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific hydroxybenzoyl motifs.
• Fine Chemical Manufacturing: Serves as a versatile reagent for introducing protecting groups in multi-step organic synthesis for flavors, fragrances, and specialty chemicals.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polyesters and resins with enhanced functionality.
• Bioconjugation & Probe Development: Utilized in biochemical research for labeling biomolecules (proteins, peptides) due to its reactive acyl chloride group.
• Material Science Research: Employed in the surface modification of nanomaterials and the creation of functional organic frameworks.

Basic Information

Product Name	Benzoyl Chloride,2,3,4-Trihydroxy-
CAS No.	355374-15-1
Molecular Formula	C7H5ClO4
Molecular Weight	188.56 g/mol
Synonyms	2,3,4-Trihydroxybenzoyl Chloride; Galloyl Chloride (common); 2,3,4-Trihydroxybenzoic Acid Chloride; 3,4,5-Trihydroxybenzoyl Chloride (isomer); Benzoyl chloride, 2,3,4-trihydroxy-; Pyrogallol-4-carboxylic acid chloride; 2,3,4-Trihydroxybenzoyl chloride
EINECS	Contact for details

Quality Control

Our Benzoyl Chloride,2,3,4-Trihydroxy- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, impurity profile, and moisture content. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from moisture, heat, and incompatible materials such as bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.