Description

Eprotirome CAS NO 355129-15-6 is a selective thyroid hormone receptor beta (TRβ) agonist, representing a significant advancement in the field of metabolic and cardiovascular therapeutics. This compound is of critical importance for pharmaceutical research and development, offering a targeted mechanism to modulate lipid metabolism without the adverse cardiac effects associated with non-selective thyroid hormone analogs. It is primarily needed by pharmaceutical companies, biotechnology firms, and advanced research institutions engaged in developing novel treatments for dyslipidemia, atherosclerosis, and other metabolic disorders.

Application

• Pharmaceutical R&D for novel lipid-lowering agents.
• Investigational studies targeting thyroid hormone receptor beta (TRβ) pathways.
• Pre-clinical and clinical development of treatments for hypercholesterolemia and mixed dyslipidemia.
• Research into therapeutic interventions for atherosclerosis and cardiovascular disease.
• Metabolic disorder research, including non-alcoholic fatty liver disease (NAFLD).
• Chemical reference standard for analytical method development and validation.
• Building block for the synthesis of related thyromimetic compounds.

Basic Information

Product Name	Eprotirome
CAS No.	355129-15-6
Molecular Formula	C₁₉H₁₅F₃N₂O₄
Molecular Weight	392.33 g/mol
Synonyms	KB2115; 3-[[3,5-Dibromo-4-[4-hydroxy-3-(1-methylethyl)phenoxy]phenyl]amino]-3-oxopropanoic Acid; 3-[[3,5-Dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy]phenyl]amino]-3-oxopropanoic Acid; GC-1; Thyromimetic KB2115; Eprotirome sodium
EINECS	Contact for details

Quality Control

Our Eprotirome is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm
Assay (HPLC)	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.