Description

Cidofovir Diphosphate Trisodium Salt is the trisodium salt of the active metabolite of the antiviral drug cidofovir. This compound is a critical nucleotide analog intermediate used in biochemical and pharmaceutical research, particularly in the study of viral DNA polymerase inhibition. It is essential for researchers and manufacturers developing antiviral therapies, especially those targeting cytomegalovirus (CMV) and other DNA viruses.

Application

• Antiviral Research & Development: A key biochemical tool for studying the mechanism of action of cidofovir and related nucleotide analogs against viral DNA polymerases.
• Pharmaceutical Intermediate: Serves as a high-purity reference standard and an advanced intermediate in the synthesis and quality control of antiviral active pharmaceutical ingredients (APIs).
• Biochemical Assay Development: Used in enzymatic assays to investigate nucleotide metabolism and the kinetics of viral enzyme inhibition.
• Virology Studies: Employed in cell-based and in vitro studies to evaluate the efficacy and selectivity of antiviral compounds.
• Metabolite Standard: Acts as an analytical standard for the quantification of cidofovir diphosphate in pharmacokinetic and pharmacodynamic studies.

Basic Information

Product Name	Cidofovir Diphosphate Trisodium Salt
CAS No.	352525-57-6
Molecular Formula	C8H11N3Na3O9P2
Molecular Weight	489.09 g/mol
Synonyms	((S)-1-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine Diphosphate Trisodium Salt; HPMPC Diphosphate Trisodium Salt; GS-504 Diphosphate Trisodium Salt; CDV-DP Trisodium Salt; (S)-HPMPC Diphosphate Trisodium Salt; Cidofovir PP Trisodium Salt; Trisodium (2-((S)-(4-amino-2-oxopyrimidin-1(2H)-yl)-1-hydroxy-3-phosphonopropoxy)methyl)phosphonate
EINECS	Contact for details

Quality Control

Our Cidofovir Diphosphate Trisodium Salt is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Meets ICH guidelines
pH (1% Solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.